4 Huge Vegas Slot Payouts — Desert Inn
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A software engineer won $39.7M on Megabucks at Excalibur in 2003. See the 4 biggest slot machine payouts in Las Vegas history.
2. Desert Inn
In January 2000, cocktail waitress Cynthia Jay-Brennan won almost $35 million playing a Megabucks machine at the Desert Inn. Unfortunately, a few weeks later, she was involved in car crash by a drunk driver which left her paralyzed and killed her sister. This started an urban legend/ myth that bad things happen to those who win big Vegas jackpots.
Total Winnings: $34,955,489.56



