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These Are the Most Expensive Hotels Rooms in Las Vegas — Palms Casino Resort

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The Palms' Empathy Suite costs $100,000 per night. Compare luxury suites at the Wynn, Cosmopolitan, Venetian, and Nobu Hotel.

These Are the Most Expensive Hotels Rooms in Las Vegas

5. Palms Casino Resort

Night view of the Palms hotel tower with illuminated "PALMS" signs and colorful rainbow-like lights on its rooftop.

The founder George Maloof outdid himself with this one. The Palms is a beautiful, newly reopened hotel with modern amenities, high-end dining options, ample rooms, and an opulent ambiance. The Empathy suite is the most expensive hotel room in the city at $100,000 a night. Also, the booking arrangement stipulates a minimum of two nights to secure this suite. It occupies 9000 square feet, and guests staying here enjoy perks like a private pool, a dedicated massage room, casino credit, a large bar, a water tank with sharks, and more.

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